Wednesday, August 20, 2008

BRCA1, BRCA2, TP53, and CDKN2A germline mutations in patients with breast cancer and cutaneous melanoma

Abstract Purpose  From epidemiological studies it appears that breast cancer (BC) and cutaneous melanoma (CMM) in the same individual occur at a higher frequency than expected by chance. Genetic factors common to both cancers can be suspected. Our goal was to estimate the involvement of “high risk” genes in patients presenting these two neoplasia, selected irrespectively from family history and age at diagnosis.

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