A phase I study of doxifluridine combined with weekly paclitaxel for metastatic gastric cancer

AbstractPurpose  Based on the synergistic effect in preclinical studies, a phase I clinical trial for the combination of paclitaxel and doxifluridine (an intermetabolite of capecitabine) was performed to determine the recommended dose for the treatment of patients with metastatic gastric cancer.